A materials science lab with high-heat ovens and fume hoods directly over the exhaust enclosure to prevent heat buildup.

Designing Materials Science Labs: MEP Essentials

A guide to effective materials science lab design—covering HVAC, pure water, gases, and more to create safe, adaptable spaces for research success

Written byScott Foster, PE
Updated | 5 min read
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Materials science is a rapidly growing field driven by the search for new materials to address a wide range of modern challenges—from developing safer, more efficient batteries to producing materials that meet the demands of quantum computing. Advancing this research requires spaces that accommodate sophisticated analytical equipment, ensure safety, and provide flexibility for future technological advancements.

However, the complexities of materials science labs often create challenges for designing the mechanical, electrical, and plumbing/piping (MEP) systems needed to perform research safely and effectively. Drawing on insights from Affiliated Engineers’ (AEI) experience renovating UL Research Institutes’ Materials Discovery Research Institute (MDRI) laboratory, the following discussion explores MEP design strategies to address the unique challenges associated with these intricate spaces.

Achieving Precision Climate Control in Materials Science Labs

Different materials science research demands varying levels of precision in temperature and humidity control. Some materials are susceptible to temperature fluctuations and require control within ±0.5°F. Achieving this level of precision involves detailed engineering, proper diffuser selection and placement, and often using computational fluid dynamics (CFD) to ensure stable conditions.

Additionally, specific analytical equipment requires process cooling for temperature control. For example, the MDRI houses equipment that relies on standalone process chillers, which presented AEI with a unique design obstacle. The chillers rejected heat in the room, and the insufficient air supply made it difficult to maintain proper cooling. As a result, MDRI required additional split-system cooling units to regulate the temperature effectively.

Optimizing Limited Ceiling Space for Complex Lab MEP Systems

A frequently overlooked design factor is the complex interplay of ceiling-mounted systems. Materials science labs often require a large network of supply and exhaust ducts to handle high air volumes, creating limited space above the ceiling. Components such as diffusers, sprinklers, lighting fixtures, occupancy sensors, overhead emergency showers, and gas detection systems compete for placement within the same 2’x2’ ceiling grid, requiring careful coordination to ensure optimal use of space.

Within the MDRI oven room, specifically, the intricacy of the required MEP systems posed potential challenges for installation during construction. The engineering team allowed the MEP systems to inform the room design and ceiling layout to ensure proper functionality, using early 3D modeling of the space to prevent costly conflicts during construction.

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Navigating Complex Utility Systems: Gas Management, Pure Water, and Compressed Air

Gas management. Materials science labs typically utilize multiple specialized gases at varying pressures and purities. The MDRI’s design featured a centralized gas rack system to support various gases while maintaining strict safety protocols. Its design established dedicated zones for different gas types—inert, flammable, or oxidizing—to ensure proper separation and risk management.

To ensure gases could be added or changed as needed, the team routed gases below the ceiling on a pipe rack for easy identification and modification. However, accommodating a large number of gases led to a wider pipe rack, which introduced challenges for light and diffuser placement in the ceiling. Detailed coordination and analysis confirmed proper lighting levels and ventilation, ensuring a safe and functional laboratory environment.

Compressed air. Utility placement can significantly impact materials science laboratory design, yet it is often overlooked. Ideally, air compressors should be located outside the lab to minimize noise, vibration, and additional heat. If compressors are placed within the lab, the design must incorporate noise and vibration isolation systems while factoring heat gain into the final cooling requirements.

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Pure water. Pure water demands within a materials science lab can vary, so including pre-treatment and point-of-use final treatment systems offers the most comprehensive design solution. This setup provides flexibility within the lab, and the point-of-use systems are easier to relocate as research needs evolve.

Closing equipment information gaps. One significant obstacle that laboratory designers and managers face is obtaining comprehensive technical information for analytical equipment. Effective lab design ultimately depends on having an accurate understanding of equipment specifications. However, the information manufacturers provide is often insufficient to fully assess MEP systems requirements. Essential details needed for MEP systems design typically include:

  • Precise connection points (type, size, and location)
  • Static pressure requirements for exhaust connections
  • Heat output under various operating conditions
  • Electrical requirements, including standby power consumption
  • Control system integration parameters

Having access to a complete equipment list with comprehensive technical specifications can help accelerate the design process and ensure MEP systems are safe and compliant.

Prioritizing Design Flexibility and Advanced Safety in Materials Labs

Take a holistic approach. Designing effective materials science laboratories necessitates a holistic approach that balances technical specifications, safety considerations, and operational flexibility. The complex interplay of systems within materials science laboratories necessitates close collaboration between laboratory managers, architects, and engineers throughout the design and construction process. 

Integrate flexibility within the design. Flexibility is also important, as change is the one constant in material sciences. Analytical equipment and material testing requirements continue to evolve. Designing for a specific application on day one must also allow for future modifications to accommodate advances in technology and research needs.

Go beyond compliance when designing for safety. Maintaining a safe environment in materials science labs requires surpassing basic regulatory compliance. Lab design should ensure the integration of often-overlooked safety features, such as:

  • Access control systems tailored to the hazard level, ensuring that only trained staff can access the lab
  • Strategically placed safety showers, with careful attention to drainage requirements
  • Water leak detection systems, particularly critical for protecting expensive analytical equipment
  • Specialized monitoring for unique hazards associated with materials research

Planning, flexibility, and innovation are key 
 To support world-class materials science research, lab managers should keep these practical design takeaways in mind:

  • Plan early with stakeholders to ensure MEP needs align with evolving research and equipment requirements.
  • Use 3D modeling during design to visualize and resolve spatial conflicts in complex ceiling and utility layouts.
  • Design for flexibility by using modular systems and adaptable utility routing that can evolve with research demands.
  • Collaborate closely with engineers and architects to balance safety, technical performance, and future adaptability.
  • Prioritize equipment data collection to prevent delays and ensure systems are sized and configured correctly.
  • Go beyond code compliance by integrating safety systems tailored to specific lab hazards and materials.
  • Anticipate future technologies by leaving room—physically and operationally—for expansion or upgrades.

FAQ

What are the biggest challenges in designing the Mechanical, Electrical, and Plumbing/Piping (MEP) systems for materials science labs?

The primary challenges stem from the need for precision climate control, managing limited ceiling space, and navigating complex utility systems.

  • Climate Control: Maintaining extremely stable temperature and humidity (sometimes ±0.5∘F) for sensitive materials and equipment is difficult. Additional complexity arises from managing the heat rejected by process cooling chillers, often requiring extra cooling units.
  • Ceiling Space: Materials labs require an extensive network of large supply and exhaust ducts, competing with lighting, sprinklers, sensors, and other fixtures for limited overhead space.
  • Utility Systems: Labs use multiple specialized gases (inert, flammable, oxidizing) requiring centralized, segregated routing, as well as complex pure water and compressed air systems.

How can designers ensure proper temperature and humidity control in materials science research labs?

Achieving the required precision often involves a multi-faceted approach:

  • Detailed Engineering: Utilizing proper diffuser selection, strategic placement, and often computational fluid dynamics (CFD) modeling to ensure stable air movement and conditions.
  • Process Cooling Integration: Accounting for the heat rejected by specialized equipment's standalone process chillers and incorporating supplemental cooling units (like split-system cooling) when the primary air supply is insufficient to manage the heat load.

What is the significance of using 3D modeling and early coordination in the lab design process?

3D modeling is a critical tool for preventing costly conflicts and ensuring functionality. Labs have complex ceiling layouts and utility routing due to the high volume of ducts, pipes, and fixtures competing for space. Using 3D modeling early allows the design team to:

  • Visualize the space and the interplay of all systems.
  • Resolve spatial conflicts (e.g., ducts versus lights, or wide gas pipe racks versus diffusers) before construction begins.
  • Ensure the design can accommodate all required MEP systems and maintain necessary safety and performance standards.

What crucial information is often missing when designing MEP systems for materials science equipment, and why is it important?

A significant obstacle is the lack of comprehensive technical information from equipment manufacturers. Effective lab design requires precise data to size and configure MEP systems safely and efficiently. Essential missing details often include:

  • Precise connection points (type, size, and location) for utilities.
  • Static pressure requirements for exhaust connections.
  • Accurate heat output under various operating conditions.
  • Detailed electrical requirements, including standby power.

Without a complete list of technical specifications, designers risk delays, improperly sized systems, and non-compliant or unsafe laboratory installations.

About the Author

  • Scott Foster, PE, LEED AP®, is a principal at Affiliated Engineers, Inc., with over 24 years of experience in the AEC industry. Scott guides projects from concept to completion while driving the firm’s growth and success in the midwest. With expertise in advanced mechanical systems, he specializes in solutions like radiant cooling, chilled beams, and geothermal strategies for data centers, research labs, and academic facilities.

    View Full Profile

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