Hyperion Analytical, the nanoparticle characterization company, is excited to announce the launch of the all-new Envision NTA Nanoparticle Size and Concentration Analyzer at Pittcon 2024 in San Diego, CA, February 26-28. The Envision realizes the full potential of the Nanoparticle Tracking Analysis (NTA) technique with dramatically improved sensitivity, lower limit of detection, dynamic range, and reproducibility compared to legacy systems. Developed to address the limitations of the previous generations of NTA/PTA instruments, the Envision enhances analytical capabilities while improving data reliability and ease of use.

The ability to measure liposomes and extracellular vesicles as small as 40nm and polymer nanoparticles below 30nm, the lower limit of detection provides a full view of sample distributions. This sensitivity allows measurement of smaller fluorescent particles without photo-bleaching, which provides a robust analysis and allows reliable speciation.

The Hyperion Analytical Envision analyzer is a significant advance over prior generation NTA instruments on the market, which have failed to evolve significantly from their initial introduction. The Envision is a clean-sheet design that overcomes the inherent limitations in legacy optical designs. The system and mechanical design was specifically targeted to broaden the range of applications allowed, from robust fluorescence studies of extracellular vesicles (exosomes) to viral counting to online monitoring of water treatment processes. Beyond enhanced sensitivity, lower detection limit, and dynamic range, the usability has been improved with a built-in syringe pump, a stable optical platform isolated from environmental vibration and a robust construction for long- term reliability.