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New Instrument Fully Automates Sample Preparation for PFAS Analysis in Drinking Water

Designed for EPA method 537.1, the Thermo Scientific Dionex AutoTrace 280 PFAS solid-phase extraction instrument delivers reliable, consistent sample preparation for the determination of PFAS in drinking water

by Thermo Fisher Scientific
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SUNNYVALE, CA — A new instrument that fully automates sample preparation for the analysis of per- and polyfluoroalkyl substances (PFAS) in drinking water by EPA method 537.1 is designed to help laboratories overcome the challenges associated with current labor-intensive manual methods. Eliminating manual steps supports laboratory cost savings and reduces the risk of errors and re-runs – improving efficiency and enhancing reproducibility.

Thermo Scientific Dionex AutoTrace 280 PFAS solid-phase extraction instrument.
Thermo Fisher Scientific

The Thermo Scientific Dionex AutoTrace 280 PFAS Solid-Phase Extraction Instrument is a high-throughput solid-phase extraction (SPE) system based on the established AutoTrace 280 instrument. The new AutoTrace 280 PFAS system is specifically designed for EPA method 537.1 and alleviates any need for the time-consuming rinsing steps before sample preparation. While fulfilling the stringent requirements of PFAS analysis, the instrument can also run other SPE methods, providing a versatile sample preparation solution for other workflows.

"PFAS are among the most persistent of today’s environmental pollutants and growing concern is putting environmental, municipal water and public health laboratories under increasing pressure to produce accurate, reliable detection with increased throughput," said Tara Tereso, vice president and general manager, ion chromatography and sample preparation, Thermo Fisher Scientific. "The AutoTrace 280 PFAS is part of Thermo Fisher’s complete range of solutions for PFAS analysis, from water collection through sample preparation, analysis and data generation, and is designed to help laboratories automate sample preparation for greater productivity and more consistent results."

The AutoTrace 280 PFAS Solid-Phase Extraction Instrument is designed to ensure performance in sample preparation for PFAS analysis in drinking water using the SPE and liquid chromatography/tandem mass spectrometry techniques designated in EPA method 537.1, and similar procedures. It extracts these analytes from large volume aqueous samples easily and efficiently, automating all four steps of SPE (conditioning, loading, rinsing, and eluting), and simultaneously processing up to six samples in two to three hours with only 15 minutes of operator involvement.

For more information on the AutoTrace 280 PFAS and Thermo Fisher’s range of solutions for PFAS analysis, please visit:

About Thermo Fisher Scientific 

Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue exceeding $25 billion. Our mission is to enable our customers to make the world healthier, cleaner, and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies, or increasing productivity in their laboratories, we are here to support them. Our global team of more than 75,000 colleagues delivers an unrivaled combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, and Patheon. For more information, please visit

Thermo Fisher Scientific

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