Content by Hamilton Robotics

Problem: Molecular biology relies on the ability to precisely target and amplify nucleic acids, and next-generation sequencing (NGS) platforms and cloning reactions benefit from precise size selection and analytical characterization of samples. For decades, researchers have used electrophoresis with agarose gels for both size selection and fragment-length distribution assessment of DNA samples for downstream assays.

Problem: ELISA assays are a workhorse assay used in pharmaceutical research and molecular diagnostic labs. This assay can be a high-volume service area for contract labs. However, many IVD labs and CROs have difficulty in costeffectively scaling their ELISA workflow to meet customer demand. This simple assay becomes deceptively complex: time sensitive steps and subtle workflow changes between different tests can be challenging to process as throughput increases. Reagent costs can cut further into tight operating margins. At some point manual processing becomes too challenging from an IVD compliance and operational perspective. Automating the laboratory’s workflow is the answer—but it can seem difficult to implement and expensive.