When it comes to lab design, especially in life science research, a contamination-free environment is crucial. Biological safety cabinets (BSCs) are built for this purpose and provide laboratory personnel, products, and the external environment with proper protection from hazardous particulates and aerosols.
In establishing or renovating a laboratory space, proper placement of equipment is highly important for their performance and effectiveness. BSCs are impacted by airflow and personnel patterns. Being aware of the right metrics to follow and optimally placing your BSCs in the lab can go a long way to ensure their containment performance and allow for appropriate process flow for scientific procedures and safety purposes.
Baker SterilGARD models
BSCs can be categorized based on their airflow patterns and levels of protection. Class II Type A2 BSCs, such as the Baker SterilGARD, provide comprehensive protection for personnel, products, and the environment. This is enabled by a combination of HEPA filtration and controlled airflow patterns, making the SterilGARD a versatile resource acceptable for use with biosafety level (BSL) 1 through 4 laboratories.
Best spacing practices for getting the most out of your BSC
How much space is required around a biosafety cabinet to maintain proper protection? Use the following chart to optimally design your BSC lab space.
Parameter | NIH DRM | NSF Standard 49 | Baker SterilGARD |
Distance to side wall | 12" / 30 cm | 6" / 15 cm | 12" / 30 cm |
Side-by-side BSCs | 40" / 100 cm | 6" / 15 cm | 12" / 30 cm |
Clearance in front of BSC | 40" / 100 cm | 40" / 100 cm | 40" / 100 cm |
Wall in front of BSC | 80" / 200 cm | 60" / 150 cm | 60" / 150 cm |
Facing BSCs | 120" / 300 cm | 100" / 250 cm | 100" / 250 cm |
Door – hinge side | 40" / 100 cm | 6" / 15 cm | 6" / 15 cm |
Door – swing side | 60" / 150 cm | 40" / 100 cm | >60" / >150 cm |
Overhead clearance | 14-18" / 35-45 cm | 12" / 30 cm | 12" / 30 cm |
Proper implementation of spacing in BSCs and associated equipment is crucial for efficient and safe laboratory practices and performance. Careful consideration of airflow dynamics can help maintain your BSC's integrity while also ensuring personnel safety.
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