Lab Manager | Run Your Lab Like a Business

California Institute of Technology

Controlling a Robotic Arm with a Patient's Intentions

Neural prosthetic devices implanted in the brain's movement center, the motor cortex, can allow patients with amputations or paralysis to control the movement of a robotic limb—one that can be either connected to or separate from the patient's own limb. However, current neuroprosthetics produce motion that is delayed and jerky—not the smooth and seemingly automatic gestures associated with natural movement. Now, by implanting neuroprosthetics in a part of the brain that controls not the movement directly but rather our intent to move, Caltech researchers have developed a way to produce more natural and fluid motions.

Do Fruit Flies Have Emotions?

A fruit fly starts buzzing around food at a picnic, so you wave your hand over the insect and shoo it away. But when the insect flees the scene, is it doing so because it is actually afraid? Using fruit flies to study the basic components of emotion, a new Caltech study reports that a fly's response to a shadowy overhead stimulus might be analogous to a negative emotional state such as fear—a finding that could one day help us understand the neural circuitry involved in human emotion. 

Chemists Create “Comb” that Detects Terahertz Waves with Extreme Precision

Light can come in many frequencies, only a small fraction of which can be seen by humans. Between the invisible low-frequency radio waves used by cell phones and the high frequencies associated with infrared light lies a fairly wide swath of the electromagnetic spectrum occupied by what are called terahertz, or sometimes submillimeter, waves. Exploitation of these waves could lead to many new applications in fields ranging from medical imaging to astronomy, but terahertz waves have proven tricky to produce and study in the laboratory. Now, Caltech chemists have created a device that generates and detects terahertz waves over a wide spectral range with extreme precision, allowing it to be used as an unparalleled tool for measuring terahertz waves.

Biochemist Sheds Light on Structure of Key Cellular 'Gatekeeper'

Facing a challenge akin to solving a 1,000-piece jigsaw puzzle while blindfolded—and without touching the pieces—many structural biochemists thought it would be impossible to determine the atomic structure of a massive cellular machine called the nuclear pore complex (NPC), which is vital for cell survival.

Unusual Light Signal Yields Clues About Elusive Black Hole Merger

The central regions of many glittering galaxies, our own Milky Way included, harbor cores of impenetrable darkness—black holes with masses equivalent to millions, or even billions, of suns. What is more, these supermassive black holes and their host galaxies appear to develop together, or "co-evolve." Theory predicts that as galaxies collide and merge, growing ever more massive, so too do their dark hearts.

Sun Sizzles in High-Energy X-Rays

For the first time, a mission designed to set its eyes on black holes and other objects far from our solar system has turned its gaze back closer to home, capturing images of our sun. NASA's Nuclear Spectroscopic Telescope Array, or NuSTAR, has taken its first picture of the sun, producing the most sensitive solar portrait ever taken in high-energy X-rays.