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DNA repair

Ribose-seq Identifies and Locates Ribonucleotides in Genomic DNA

by Georgia Institute of Technology
Ribonucleotides, units of RNA, can become embedded in genomic DNA during processes such as DNA replication and repair, affecting the stability of the genome by contributing to DNA fragility and mutability. Scientists have known about the presence of ribonucleotides in DNA, but until now had not been able to determine exactly what they are and where they are located in the DNA sequences.