Researchers Solve Long-Standing Biological Search Problem
How can a cell find the correct DNA template to mend broken DNA given how busy the interior of the cell is?
DNA repair
Researchers Create Bioluminescent Tag to Detect DNA Break Repair
The bioluminescent repair reporter-based system can be used to monitor DNA repair pathways directly in animals as well as cell lines
This Enigmatic Protein Sculpts DNA to Repair Harmful Damage
Scientists have determined how a protein called XPG binds to and reshapes damaged DNA, illuminating its role in averting genetic disease and cancer
Decoding the DNA Repair Process
KU Cancer Center researchers are developing approaches to manipulate the DNA damage response to treat and prevent disease
How Cells Detect, Mend DNA Damage May Improve Chemotherapy
Targeting pathway could increase potency of some current drugs
Berkeley Lab Scientists Map Key DNA Protein Complex at Near-Atomic Resolution
Achievement using cryo-electron microscopy to aid gene research and drug development
Shape and Size of DNA Lesions Caused by Toxic Agents Affects Repair of DNA
SDSC’s ‘Gordon’ helps describe complex process that’s fundamental to cancer initiation
The Carpenter Enzyme Gives DNA the Snip
This enzyme—known as Flap endonuclease 1, or FEN1—is often highly overexpressed or faulty in cancer and other types of diseases
New Findings Shed Light on Fundamental Process of DNA Repair
Researchers now know how key proteins get where they need to be to facilitate the process
A New Look at How Cells Repair DNA Damage
Time-lapse imaging helps provide new insights into process