KU Cancer Center researchers are developing approaches to manipulate the DNA damage response to treat and prevent disease
Targeting pathway could increase potency of some current drugs
Achievement using cryo-electron microscopy to aid gene research and drug development
SDSC’s ‘Gordon’ helps describe complex process that’s fundamental to cancer initiation
This enzyme—known as Flap endonuclease 1, or FEN1—is often highly overexpressed or faulty in cancer and other types of diseases
Researchers now know how key proteins get where they need to be to facilitate the process
CURRENT ISSUE - October 2025
Move Beyond Policies to Build a Lab Culture Where Safety is Second Nature