gene activity

Researchers rethink the central dogma of molecular biology and how cells regulate transcription and translation

Vitamin C affects whether genes are switched on or off inside mouse stem cells, suggesting that it could may play a fundamental role in helping to guide normal development in mice, humans and other animals, a team led by UC San Francisco researchers has discovered.

Whitehead Institute researchers report that common assumptions employed in the generation and interpretation of data from global gene expression analyses can lead to seriously flawed conclusions about gene activity and cell behavior in a wide range of current biological research.