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Increase Accuracy in Molar Mass Averages by Gel Permeation Chromatography

by Tosoh Bioscience
Gel permeation chromatography (GPC) is the most widely accepted and used analytical method for  obtaining molar mass averages of both synthetic and biopolymers. Traditionally, molar mass averages are obtained via a peak position calibration involving a series of standards of known molar mass and chemistry analyzed by GPC coupled to a differential refractive index (RI) detector.