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Product Application News

Using the NanoDrop 3300 Fluorospectrometer for Cancer Research Applications

Epigenetic modifications are defined as heritable information other than nucleotide sequences (1) that have the ability to control how and when transcription takes place. DNA methylation and secondary DNA structures such as DNA Gquadruplexes are among the epigenetic modifications currently under study because of their common associations with cancer (1,2).

Automated Detection of Drug-Induced Lysosomal Cytotoxicity - Automation of the Lyso-ID Red Assay Using the EL406 Combination Washer Dispenser

Almost all drug compounds will elicit deleterious effects on cells at some concentration. Lysosome perturbation as a result of ion trapping of amine containing compounds has been demonstrated to cause the formation of autophagosomes and autophagic cytopathology. Here we describe the use of the EL406 Combination Washer Dispenser to automatically aspirate media, wash cells and dispense reagents for the Lyso-ID Red Detection kit, part of the CELLestial Live Cell Analysis platform from Enzo Life Sciences.