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Whitehead Institute

Direct Generation of Neural Stem Cells Could Enable Transplantation Therapy

by Nicole Giese Rura - Whitehead Institute
Induced neural stem cells (iNSCs) created from adult cells hold promise for therapeutic transplantation, but their potential in this capacity has been limited by failed efforts to maintain such cells in the desirable multi-potent NSC state without continuous expression of the transcription factors used initially to reprogram them.