Hydrogen, as a carrier gas for GC, can be generated at low pressure on a local basis to provide significant safety and convenience compared to the use of tank gas.

Using Hydrogen for Gas Chromatography

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While helium’s availability has improved there are still concerns surrounding supply stability and rising costs, especially for gas chromatography (GC) workflows where it’s the industry standard carrier gas. To manage budgets and ensure operational continuity many lab managers are exploring alternatives like hydrogen and nitrogen. However, this shift requires a deep understanding of the key differences in performance—including efficiency, speed, and resolution—and safety and sustainability considerations.&nbsp;<figure class="fr-image-container fr-quarter fr-right" data-id="froala-uploading-image-1731524327266"><picture><img loading="lazy" title="Beyond Helium: Carrier Gas Alternatives for Gas Chromatography" alt="Beyond Helium: Carrier Gas Alternatives for Gas Chromatography" src="https://cdn.labmanager.com/assets/image/52583/peak-cover-l.jpg" data-id="52583" class="fr-fil fr-dib"></picture><figcaption class="fr-figcaption"> </figcaption></figure>Hydrogen offers greater efficiency than helium at high linear velocities, allowing for increased throughout, but its flammability poses substantial health and safety concerns. Nitrogen, in comparison, has a lower optimal linear velocity, making it suitable for GC applications where high efficiency isn’t essential. Traditionally, both gases are supplied in cylinders. These cylinders are subject to price fluctuations, delivery fees, and safety hazards from potential leaks and handling. For many labs, gas generators provide a safer, more sustainable, and cost-effective alternative to gas cylinders, delivering a continuous, on-demand supply of hydrogen or nitrogen.&nbsp;This resource provides lab managers with a closer look at sustainable carrier gas options, along with practical steps for transitioning from helium to hydrogen or nitrogen. With a clear understanding of the strengths and limitations of each carrier gas and gas generation technology, labs can make informed, strategic decisions that enhance the reliability, efficiency, and safety of their GC workflows.&nbsp;Download this resource guide to discover:&nbsp;<ul><li>Performance comparisons of hydrogen and nitrogen to guide carrier gas selection</li><li>Key considerations for the safe and reliable use of hydrogen</li><li>A list of ASTM, USP, and EPA gas chromatography methods adapted for hydrogen and nitrogen</li><li>Guidance for transitioning gas chromatography systems from helium to alternative gasses</li><li>A detailed overview of in-lab gas generation technologies</li></ul>

Beyond Helium: Carrier Gas Alternatives for Gas Chromatography

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Gas Chromatography

Using Hydrogen for Gas Chromatography

Turning Safety Principles Into Daily Practice

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