Cytation™ 5 is a uniquely integrated, configurable system that combines automated digital widefield microscopy with conventional multi-mode microplate detection to provide phenotypic cellular information and well-based quantitative data. 

Biochemical and cell based assays using a microplate reader provide quantitative data on ex vivo cell behavior, while viewing cells with a microscope allows researchers to see cellular and intra-cellular processes via fixed cells or with live cell imaging.  Both methods are equally important to life science research and the drug discovery process.  Together, these methods provide valuable, content rich data that otherwise requires the expense of multiple instrumentation. 

Assays using immortalized cell lines and plastic labware have been used for decades as an in-vitro mimic of how a putative drug may work in the human body. 

BioTek congratulates Dr. Jeff Peterson of the Fox Chase Cancer Center in Pennsylvania for winning a new Cytation™ 3 Cell Imaging Multi-Mode Reader in BioTek's "Think Possible" Application Contest. Entrants were judged on a short essay that they submitted, detailing the application that they think is possible for their specific research using the Cytation 3. As an Associate Professor, Dr. Peterson studies chemical biology and kinase signaling in cancer.

BioTek's Think Possible video, created by Hen House Media, was recently awarded a Silver Telly Award in the "Non-Broadcast, Motivational" category as part of the 35th Annual Telly Awards. Standing out from over 12,000 entries, the Silver Telly is the highest honor bestowed upon film and video productions, and awarded to less than 10 percent of entries.

Problem: There is little doubt that cell-based assays are becoming a mainstay across the pre-clinical drug discovery process. Many of these assays are end-point based, where live cells are cultured in microplates, incubated with compounds of

Synergy NEO is BioTek’s newest development in multi-mode microplate readers. Designed specifically for today’s screening and core laboratories, NEO has all the features you would expect from an HTS instrument.

For nearly 30 years, BioTek has led the market in developing microplate washing technologies, and is well recognized for the industry standard ELx405™ Microplate Washer.

Bulk microplate-based liquid dispensing instruments typically use peristaltic pumps or microprocessor- controlled syringe pumps to perform reagent and cell dispensing. Each pump type has advantages and disadvantages depending on the reagent used and the lab's needs.

For nearly 30 years, BioTek has led the market in developing microplate washing technologies, and is well recognized for the industry standard ELx405™ Microplate Washer.

Highly concentrated nucleic acid and protein samples must be diluted before they can be read on most absorbance-based spectrophotometers, and conversely, diluted samples must be concentrated to within the spectrophotometer’s dynamic range before reading.