image of a gloved hand against various lab hazard symbols emphasizing the importance of accident prevention in the laboratory

Preventing accidents in the laboratory is an ongoing responsibility shared by all who work in a lab setting.

iStock | Kittisak Kaewchalun

Preventing Accidents in the Laboratory: Essential Safety Measures and Best Practices

Accidents in the laboratory are often the result of carelessness or ignorance either by you or by your neighbors. Stay alert and pay constant attention to your own and to your neighbors' actions. 

Updated | 4 min read
Register for free to listen to this article
Listen with Speechify
0:00
4:00

Accidents in the laboratory often result from carelessness or ignorance—either by you or by those around you. From chemical spills to fires and from cuts to toxic fume inhalation, each incident can have serious consequences for your health and safety. Whether you’re a seasoned scientist or a newcomer to the lab, staying alert and planning every operation before you perform it is key to preventing unexpected hazards.

Below, we break down the most common lab accidents and outline the laboratory safety measures you need to practice daily. By taking these guidelines seriously and using the right personal protective equipment (PPE), you can cultivate a culture of vigilance that keeps both you and your colleagues safe.

Lab manager academy logo

Get training in Employee Engagement and Wellbeing and earn CEUs.

One of over 25 IACET-accredited courses in the Academy.

Certification logo

Employee Engagement and Wellbeing course


Understanding Common Laboratory Accidents

1. Fire Hazards

Open flames in the lab are a major source of accidents. Treat any flammable liquid like gasoline—use extreme caution around flames or sparks.

  • Heating Solvents: Never heat organic solvents over an open flame. Use a steam bath in a fume hood instead.
  • Volatile Chemicals: Liquids such as ether, acetone, or benzene should never be stored or used in open containers. These vapors can travel along surfaces and ignite when they encounter a flame.
  • Emergency Equipment: Know where your fire extinguisher and safety shower are located. In a fire emergency, quick access to these tools can save lives.

2. Explosions

Explosion risks often arise from closed systems and improper venting. When heat or a reaction builds pressure in an enclosed container, the results can be catastrophic.

  • Venting: Always ensure that the distillation apparatus or reaction setups are vented properly.
  • Flying Debris: Explosions send glass shards and hot chemicals flying, which can cause severe injuries. Proper shielding and wearing PPE significantly reduce the risk.

3. Chemical and Thermal Burns

Corrosive acids, alkalis, and some organic chemicals can cause severe burns on contact. Additionally, hot plates and heated surfaces pose thermal burn risks.

  • Spills: Clean up chemical spills immediately—some substances may corrode surfaces and remain hazardous even after drying.
  • Hot Surfaces: Always assume a hot plate is still hot, even after it’s turned off.
  • Protective Gear: Wear safety goggles, gloves, and lab coats to minimize skin and eye exposure.

4. Cuts

The most common accident in any lab is a cut from broken glass—often when forcing glass tubing or thermometers through tight rubber stoppers.

  • Proper Sizing: Make a suitable hole in the stopper and lubricate the glass before inserting.
  • Technique: Use a gentle, twisting motion rather than forceful pushing. When possible, pull the glass instead of pushing it.
  • Common Injuries: Improper manipulation can lead to severed nerves or tendons, so never rush when handling glassware.

5. Absorption of Chemicals

Not all chemicals cause instant burns or irritation. Many toxic chemicals pass through the skin silently, causing cumulative damage over time.

Interested in lab health and safety?

Subscribe to our free Lab Health & Safety Newsletter.

Is the form not loading? If you use an ad blocker or browser privacy features, try turning them off and refresh the page.

  • Protective Gloves: Gloves offer an extra layer of defense but can become permeable to certain chemicals without visible deterioration. Change gloves immediately if they come into contact with reagents.
  • Avoid Face Contact: Never touch your eyes or face in the lab before washing your hands thoroughly.

6. Inhalation of Toxic Fumes

Many common solvents and reagents emit hazardous vapors. Prolonged exposure can lead to respiratory irritation, organ damage, or long-term health problems.

  • Fume Hoods: Use a fume hood for solvent evaporation and other chemical processes that release vapors.
  • Irritants: Some compounds, like acetyl chloride or benzyl chloride, severely irritate membranes and eyes, so never sniff chemicals directly.

7. Ingestion of Chemicals

While less common, ingestion of toxic substances can be fatal or cause serious medical issues.

  • Pipetting: Always use rubber bulbs, never mouth pipet.
  • Contamination: Keep food and drinks out of the lab and never use lab utensils as substitutes for kitchenware.
  • Hand Washing: Wash your hands before eating, drinking, or touching your mouth, especially after removing gloves.

Core Laboratory Safety Practices

  • Plan and Understand: Read through your experiment or procedure thoroughly. Think about each step’s potential hazards before you begin.
  • Label and Store Properly: Incorrect or unlabeled containers can lead to dangerous mix-ups. Always label your chemicals accurately and store flammable or volatile substances in designated cabinets.
  • Stay Alert: Keep an eye on your neighbors as well as your own actions. Ignorance or carelessness in a shared lab can affect everyone’s safety.
  • Use the Right Tools: From heat-resistant glass to fume hoods, ensure you are using the correct laboratory equipment for each process.
  • Wear Personal Protective Equipment (PPE): Standard PPE—goggles, lab coats, glovesclosed-toe shoes—is non-negotiable. Additional gear may be necessary for more hazardous tasks.
  • Know Emergency Exits and Equipment: Familiarize yourself with the location of fire extinguishers, safety showers, eyewash stations, and emergency exits. In a crisis, seconds matter.

Frequently Asked Questions (FAQ)

1. Why is planning so crucial for preventing accidents in the laboratory?

Planning helps you anticipate potential hazards and take proactive steps to mitigate them. By reviewing experiment details beforehand, you can identify the right PPE, equipment, and safety protocols needed to avoid an accident.

2. Can wearing gloves eliminate all chemical exposure risks?

Gloves offer an additional barrier against toxic or corrosive substances, but they are not fail-proof. Some chemicals can permeate glove material. If a spill occurs on your gloves, remove them, wash your hands, and replace them immediately.

3. Is it ever acceptable to mouth pipet chemicals in a lab?

No. Mouth pipetting is strictly prohibited. Always use a pipet bulb or an automated pipetting system to avoid accidentally ingesting or inhaling harmful substances.

4. What should I do if I see someone ignoring lab safety protocols?

Safety is everyone’s responsibility. Politely remind them or inform a lab supervisor if you see any violation. Ignoring unsafe practices can lead to injuries, fires, or chemical exposure for everyone present.


Conclusion

Preventing accidents in the laboratory is an ongoing responsibility shared by all who work in a lab setting. From avoiding fires to minimizing chemical burns and from guarding against explosions to preventing toxic exposures, every precaution matters. These laboratory safety measures protect not only your own health but also the well-being of your colleagues.

Remember:

  • Stay alert—your and your neighbors’ actions both matter.
  • Plan ahead—understand the steps and consequences before you act.
  • Use proper equipment and PPE—don’t cut corners when it comes to safety.

By staying informed, prepared, and vigilant, you ensure a safer, more efficient work environment—one where both science and safety thrive.

About the Author

  • Trevor Henderson headshot

    Trevor Henderson, PhD

    Trevor Henderson BSc (HK), MSc, PhD (c), is the creative services director at Lab Manager.  He has more than two decades of experience in the fields of scientific and technical writing, editing, and creative content creation. With academic training in the areas of human biology, physical anthropology, and community health, he has a broad skill set of both laboratory and analytical skills. Since 2013, he has been working with LabX Media Group developing content solutions that engage and inform scientists and laboratorians. He can be reached at thenderson@labmanager.com.

Related Topics

Loading Next Article...
Loading Next Article...

CURRENT ISSUE - January/February 2025

Energizing Leadership in Action

The science-backed behaviors that help leaders inspire thriving teams and organizations

Lab Manager January/February 2025 Cover Image