“This research provides insight into the mechanisms of early cancer spread and may shed light into unexplained phenomena—among them, why as many as five percent of cancer patients worldwide have cancer metastases but no original tumor"
FACT, a highly sought target of cancer drugs, is involved in many cellular processes including gene regulation and cancer development, but the mechanism of its action remained a mystery
Problem: Alterations in the proteome—including changes in protein expression, function, or localization—play a significant role in the development of cancer and other diseases.