A ‘scanner’ inside cells decides whether or not so-called flawless DNA repair, which protects against cancer, is launched

KU Cancer Center researchers are developing approaches to manipulate the DNA damage response to treat and prevent disease

Targeting pathway could increase potency of some current drugs

Findings suggest that ribosomal DNA copy number could be used to predict which cancers will be sensitive to DNA-damaging chemotherapeutics

SDSC’s ‘Gordon’ helps describe complex process that’s fundamental to cancer initiation

This enzyme—known as Flap endonuclease 1, or FEN1—is often highly overexpressed or faulty in cancer and other types of diseases

In laboratory experiments, some in human cells and others in mouse cells, researchers found that the process for copying mtDNA (or replication), an essential aspect to energy production, is prone to stalling

A study in the Journal of the American Chemical Society reports that these novel components can damage cells when they are exposed to light

Team studied self-assembled complexes of DNA wrapped around single-wall carbon nanotubes utilizing a special technique

Utah chemists look for precursors to disease mutations