DNA damage

Decoding the DNA Repair Process

by The University of Kansas Cancer Center

KU Cancer Center researchers are developing approaches to manipulate the DNA damage response to treat and prevent disease

The Carpenter Enzyme Gives DNA the Snip

by King Abdullah University of Science & Technology

This enzyme—known as Flap endonuclease 1, or FEN1—is often highly overexpressed or faulty in cancer and other types of diseases

Roots of Related Genetic Diseases Found in Cell Powerhouses

by NYU Langone Medical Center

In laboratory experiments, some in human cells and others in mouse cells, researchers found that the process for copying mtDNA (or replication), an essential aspect to energy production, is prone to stalling