Drug Discovery

A Washington University in St. Louis drug discovery program has received three grants totaling more than $5 million from the National Institutes of Health (NIH) to develop new therapeutics for respiratory diseases. The target illnesses range from the common cold to life-threatening lung disease.

Enzymes are catalysts that speed up chemical reactions in living organisms and control many cellular biological processes by converting a molecule, or substrate, into a product used by the cell. For scientists, understanding details of how enzymes work is essential to the discovery of drugs to cure diseases and treat disorders.

The pharmaceutical industry has withdrawn from the ‘antibiotic space.’ Is it time for research universities to step in?

Thermo Fisher Scientific has developed a high-resolution hydrophobic interaction chromatography (HIC) method that can separate a fusion protein from a truncated version and a structural isomer.














