Drug Discovery
Scientists have created a new way of screening compounds that is more sensitive than existing methods, opening up the possibility of finding new drugs for many diseases
Systematic approach could help bring drug discovery ‘back to nature’
As a multidisciplinary activity, drug discovery relies on a range of life science analytical and processing platforms.
Western blotting separates proteins by size and shape with an electric field applied to a gel, and then targeted proteins are stained with antibodies
Device can do the functional equivalent of high-throughput compound screening on an ultra-miniaturized scale
New 2,000-square-foot laboratory and office suite is a hub for research across the entire UWM campus,
Scientists peel helpful and harmful properties of a natural substance apart, harnessing the “sugar code” that lets viruses enter cells
"Only a fraction of drugs that show promise in animals end up proving safe and effective in humans," lead researcher says
New software programs should help identify potential avenues for improved drug treatments for diabetes and other diseases
Most drug discovery efforts begin with a biological target—the molecule inside the body whose activity the drug is expected to enhance or diminish. Assurance that the target is pharmacologically accessible and responsible in some way for the disease in question is based on target validation studies.
