HPLC Sample Prep

Using the Porvair SLE plate, high analyte recovery, free of proteins and phospholipids, is routinely obtainable without the need for offline steps such as protein precipitation.

Karyn M. Usher is an analytical chemist in the Department of Natural Sciences at Metropolitan State University in Saint Paul, MN. At Metro State, her research has focused on sample preparation for the determination of analytes in complex matrices by high performance liquid chromatography.

Derek Wachtel, scientist in the DMPK department at Ironwood Pharmaceuticals, and Mingliang Bao, PhD, senior scientist at Labstat International ULC, talk to contributing editor Tanuja Koppal, PhD, regarding various issues they face with sample prep in their laboratories. They both stress that sample prep is very important and a necessary step in any analysis and with newer technologies making it easier and faster to accomplish, there should be no reason to ignore or overlook it.















