Initial demonstrations yield compounds with promise for treating COPD, cystic fibrosis, and other lung disorders

American and European researchers publish study in Nature Medicine reporting a new, single treatment option for cystic fibrosis patients

Mouse studies find increased airway resistance and inflammation even after weaning

University of North Carolina scientists found that mucin proteins, which make mucus thick and sticky, fail to unfold properly in the airways of people with cystic fibrosis. And they found the lack of water in the lung can trigger the misfolding mucins

Scientists can now grow 3-D models of various organs from stem cells, creating new ways to study disease

“We’re interested in seeing if there are things we can do to strengthen the natural defenses of the host to help them fight the infection more effectively,” said research team's leader.

The social amoeba, Dictyostelium discoideum (or “Dicty”), is a great model for human COPD

Surprising findings emerge from U-M microbiome research

Human lung organoids may help scientists learn more about lung diseases, test new drugs.

Carnegie Mellon University professor Keith Cook has received a four-year, $2.4 million grant from the National Institutes of Health (NIH) to support research and development of artificial lungs that patients may use long term in the comfort of their own homes while waiting for a lung transplant. Cook, an associate professor in the Department of Biomedical Engineering, will lead the project and collaborate with researchers from the University of Washington, Columbia University and Allegheny General Hospital in Pittsburgh.