The findings, published July 27 in Cell, reveal for the first time components of a G protein–coupled receptor (GPCR) named rhodopsin bound to a signaling molecule called arrestin, both crucial pieces of the body’s intricate cellular communication network
Through the technology—modeling a human heart on an engineered chip and measuring the effects of compound exposure on functions of heart tissue using microelectrodes—researchers hope to decrease the time needed for new drug trials