Product Resource: Insights
Things to consider when starting or running a cell culture laboratory
Environmental testing had been a sleepy marketplace until the U.S. Environmental Protection Agency began issuing strict regulations for air, soil, and water in the 1970s. Environmental law spawned thousands of large and small laboratories, many of which had been operating in nonenvironmental industries.
In 1964, University of Utah chemistry professor J. Calvin Giddings enunciated a theoretical platform, “unified separation science,” that could confer the resolving power of GC to LC. Giddings’ model combined the higher mobile phase diffusion and efficiency of GC with LC’s higher selectivity via orthogonal separation modes. His vision has been made a reality through supercritical fluid chromatography (SFC), which uses supercritical or subcritical carbon dioxide as the mobile phase.
“Fun new tools,” particularly in mass detection, have encouraged a new conversation among separation scientists, says Nicholas Hall, national sales director at LECO (St. Joseph, MI). “Every time this occurs, the instrument vendors engage in the equivalent of an arms race, where the battles are fought over specifications— more resolution, greater fragmentation capability.” But the real discussion has recently involved the very nature of chromatography, Hall says. “Just as important as the tool used for detection on the back end is the time and optimization that goes on at the front end.” Thus the resurgence of basic chromatography optimization, the application of solid analytical chemistry, and a focus on chromatography as the optimization of mass spectrometers. “If you have good separation and good sample preparation, and that goes into the MS, then you’re really optimizing the mass spectrometer’s capabilities.”
Our EXPERT: Kimberly Moser Instructional Laboratory Manager University of Oklahoma
Through research, testing, care, and education, The University of Texas MD Anderson Cancer Center, located in Houston, Texas, takes an integrative approach to cancer. We speak with Pramila Sood, lab administrator for the Department of Laboratory Medicine, about the unique management issues at the Center.
Allowing democratized access to advanced data products
A drive toward more openness and accessibility
