University of North Carolina at Chapel Hill School of Medicine

Researchers Create DNA Repair Map of the Entire Human Genome

by University of North Carolina at Chapel Hill School of Medicine

The new experimental assay can help scientists find the precise locations of repair of DNA damage caused by UV radiation and common chemotherapies. The invention could lead to better cancer drugs or improvements in the potency of existing ones.

Scientists Overturn Dogma on the Plague

by University of North Carolina at Chapel Hill School of Medicine

The current outbreak of the plague in Madagascar shines a light on the need for new approaches to treat the ancient pathogen. A new UNC study unexpectedly unravels a long-held theory on how a fleabite leads to infection.

Largest Cancer Genetic Analysis Reveals New Way of Classifying Cancer

by UNC Lineberger Comprehensive Cancer Center

Researchers with The Cancer Genome Atlas (TCGA) Research Network have completed the largest, most diverse tumor genetic analysis ever conducted, revealing a new approach to classifying cancers. The work, led by researchers at the UNC Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill and other TCGA sites, not only revamps traditional ideas of how cancers are diagnosed and treated, but could also have a profound impact on the future landscape of drug development.

The Signal and the Noise

by Mark Derewicz-University of North Carolina Newsroom

Henrik Dohlman, PhD, discovered why seemingly identical cells might react differently to the chemical signals inside our bodies and the drugs we use to battle diseases.