University of North Carolina at Chapel Hill School of Medicine

The new experimental assay can help scientists find the precise locations of repair of DNA damage caused by UV radiation and common chemotherapies. The invention could lead to better cancer drugs or improvements in the potency of existing ones.

Using a weak electric current to alter a specific brain activity pattern, UNC School of Medicine researchers increased creativity in healthy adults. Now they’re testing the same experimental protocol to alleviate symptoms in people with depression.

The current outbreak of the plague in Madagascar shines a light on the need for new approaches to treat the ancient pathogen. A new UNC study unexpectedly unravels a long-held theory on how a fleabite leads to infection.

Scientists from UNC-Chapel Hill have created a new way to investigate epigenetic mechanisms important in diseases ranging from Alzheimer’s to cancers.

For the first time, UNC neuroscientist Garret Stuber, PhD, imaged activity patterns of individual brain cells in freely moving mice to link specific basic behaviors to particular neurons.

Researchers with The Cancer Genome Atlas (TCGA) Research Network have completed the largest, most diverse tumor genetic analysis ever conducted, revealing a new approach to classifying cancers. The work, led by researchers at the UNC Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill and other TCGA sites, not only revamps traditional ideas of how cancers are diagnosed and treated, but could also have a profound impact on the future landscape of drug development.

Henrik Dohlman, PhD, discovered why seemingly identical cells might react differently to the chemical signals inside our bodies and the drugs we use to battle diseases.

UNC biochemists resurrect “molecular fossils” to conduct experiments that undercut the predominant scientific theory of how life began on Earth.