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Dawn is arriving. The crisp aroma of meadow flowers fills the air and the crowd inhales deeply to capture the scent, if only for a moment. They wait. Backlit by the rising sun, the anointed leader surges into view and a mighty cheer erupts from the crowd, deafening in the celebration of their chosen leader. Raising a hand, asking for quiet attention, the leader guides the prancing steed, resplendent in silver and highly polished leather, up and down the front lines, looking deeply into the eyes of those who have chosen to follow.

Scott Martin, Ph.D., team leader for RNA interference (RNAi) screening at the National Institutes of Health, Center for Advancing Translational Sciences, talks to contributing editor Tanuja Koppal, Ph.D., about recent trends in the use of different types of cells and reagents for screening drug targets and cellular pathways.














