
PHILADELPHIA, PA — January 25, 2021 — Opertech Bio, Inc., today announced the publication of a seminal research article describing the application of its pioneering TāStation® technology to the pharmacological characterization of human taste discrimination. The findings are published in the peer-reviewed Journal of Pharmacology and Experimental Therapeutics, JPET.
The paper, entitled "Rapid throughput concentration-response analysis of human taste discrimination," is the first to quantitatively define the concentration-response function for human taste discrimination, a crucial step in understanding the relationship between receptor activity and taste sensation. The paper is authored by the Opertech research team of R. Kyle Palmer, Mariah M. Stewart, and John Talley. The complete article is available at: DOI: https:/
"The paper provides a rigorous scientific validation of TāStation® technology in the context of threshold sensory measurements and concentration-response analysis of sucrose and other sweeteners. The results are entirely consistent with receptor occupancy theory, implying that the taste discrimination concentration-response function is a direct reflection of the underlying activity of taste receptors" said Palmer, Opertech's chief science officer and lead author on the paper. "The methodology enabled by the TāStation® produced remarkable test-to-test repeatability of results, which proved critical for statistical resolution of effects in small groups of subjects and even among individual participants," he added.
- This press release was supplied by Opertech Bio. It has been edited for style