In biopharmaceutical research and manufacturing, many processes involve sophisticated separations. One of the most advanced separation technologies is ultra-high-performance liquid chromatography (UHPLC). “There are two reasons to use UHPLC,” says Ken Cook, sales support expert, bioseparations and bio market Europe for Thermo Fisher Scientific (Waltham, MA). “The first is speed, and the second is resolution.”

Instrument driver exchange enhances laboratory efficiency, flexibility.

Over the past several decades, the progress in micro fabrication technology has revolutionized the world in such fields as computing, signal processing, and automotive manufacturing.

Harm Moes is technical support engineer at SGS in the Netherlands. Mr. Moes has 13 years of experience in analytical instrumentation and held several technical positions with an analytical instrument supplier before joining SGS. At SGS, he provides technical support to the SGS oil, gas, and chemical labs in the Netherlands. That includes implementation and validation of new instrumentation, techniques, and methods, and instruction and training of laboratory personnel.

Sports is big business, which is why leagues and federations are desperate to keep their franchises honest. In the US, Major League Baseball (MLB) received a record $9 billion in revenues in 2014, while the National Football League took in close to $10 billion. 

Once gas chromatography (GC) separates a sample into its component parts, a detector identifies them. All detectors provide certain benefits and struggle with some limitations. Whether some feature is beneficial or detrimental, however, depends on the sample and the application.

Two cannabis testing labs from Colorado share their thoughts on how the state’s emerging recreational marijuana industry has affected them.

Greg Martin is president of Complectors Consulting (www.complectors.com), based in Pottstown, PA, which provides consulting and training in the area of pharmaceutical analytical chemistry. Mr. Martin has over 25 years of experience in the pharmaceutical industry and was director of pharmaceutical analytical chemistry (R&D) for a major PhRMA company for a number of years. In addition, he has volunteered for the U.S. Pharmacopeia for over 10 years, and currently serves as vice chair of the General Chapters—Physical Analysis Expert Committee and also serves on expert panels on Validation and Verification; Weights and Balances’ Residual Solvents; and Use of Enzymes for Dissolution Testing of Gelatin Capsules.

Using compressed gases in the laboratory can be dangerous if they are not handled properly. Many gases can be explosive, flammable, corrosive, and toxic. Because the gases are under high pressure in tanks and cylinders, any release of gas can spread quickly and endanger lab personnel—including the possibility of
death from explosion or asphyxiation. Less-deadly safety risks include physical injuries from mishandling tanks, especially to the hands, feet, and lower back.

Portable gas chromatography (pGC) is all about tradeoffs. Users demand value, reliability, ease of use, ergonomics, and measurement quality but with analysis limited to gases.

Working in conjunction with customer, Daimler AG, Thermo Fisher Scientific has developed an automated in-line matrix elimination technique that simplifies the determination of trace sodium in non-water-miscible liquids such as diesel, biodiesel, and regular petroleum fuels.

Thermo Fisher Scientific has developed an ion chromatography method with suppressed conductivity detection for sensitive determination of inorganic anions and carboxylic acids (fluoride, acetate, formate, mesylate, chloride, nitrate, succinate, malonate, sulfate, and oxalate) in airborne particulate matter (PM2.5).