Software

Mechanical sample lysis is rapidly becoming the preferred sample preparation method in life science labs for the isolation of DNA, RNA, proteins, metabolites and other small molecules because the elimination of chemicals, enzymes, and detergents minimizes the introduction of potential inhibitors to downstream processes. The FastPrep-24 5G™ (Fig. 1) is the newest innovation in beat-beaters and produces the fastest lysis of even the most difficult samples.

Filters vs. Monochromators - When using a microplate reader, these are the two options to filter light into monochromatic wavelengths. Filters offered higher performance because of greater light transmission and wider bandwidths; monochromators offered greater flexibility, no new filters were needed for each new assay.

Electronic laboratory notebooks (ELNs), one component of a lab’s information infrastructure, help laboratories capture and manage knowledge, streamline data management, protect intellectual property and foster collaboration. Both non-specific/generic ELNs (which compete directly against paper notebooks) & application/task-specific ELNs exist, each with their own fans.

Steve Thomas, an investigator within the Drug Metabolism and Pharmacokinetics department at GSK, talks to contributing editor Tanuja Koppal, PhD, about his experiences implementing a database of
metabolic knowledge that helps the company store, share, and search data around the globe. The process involved analyzing internal needs, evaluating several options, and finding the right informatics solution to give GSK scientists access to each other’s findings to prevent error, repetition, or inefficiency.














