Biological Sciences

Cloudy tap water may have a greater effect for California’s rural immigrants than merely leaving behind a bad taste, according to a new policy brief released by the Center for Poverty Research at the University of California, Davis.

Problem: At the crossroads of understanding cell physiology, disease pathology and etiology lies cell metabolism, encompassing the cellular set of life-sustaining chemical transformations. Dysregulation of cell metabolism is now known to be a common component of cancer, immunology, obesity, diabetes, and neurodegenerative disease. This is because mitochondrial respiration and glycolysis are the major sources of life-sustaining and biosynthetic processes for the cell, specifically energy in the form of ATP (adenosine triphosphate) and macromolecules such as membranes, nucleotides, transporters, organelles, etc. Metabolic pathways are increasingly considered as potential therapeutic targets. Therefore, the ability to measure and understand cellular bioenergetics can provide valuable insight into disease and contribute to the potential identification of drug discovery targets.

Forest Rohwer, PhD, is a professor in the Department of Biology at San Diego State University. He is a fellow of the American Academy for Advancement of Science (AAAS), American Academy of Microbiology
(AAM), and Canadian Institute for Advanced Research (CIFAR). He led the development of viromics,” which involves isolating and sequencing the RNA/DNA from all the viruses in a sample. From this data, it is possible to determine what types of viruses are present and what functions they are encoding. Dr. Rohwer uses viromics to study ecosystems ranging from coral reefs to the human body and has shown that most genomic diversity on the planet is viral. Dr. Rohwer has published more than 150 peer-reviewed articles, was awarded the International Society of Microbial Ecology Young Investigators Award in 2008, and is listed as one of the World’s Most Influential Scientific Minds (Thomson Reuters 2014).

Linda Wegley Kelly, PhD, a marine microbial ecologist in the Department of Biology at San Diego State University, talks to contributing editor Tanuja Koppal, PhD, about what has changed in the field since 2001, when she started working in the lab. While genomic and sequencing technologies have become easier and cheaper, the work on the bioinformatics side has now become more tedious in terms of the volume of data that needs to be analyzed. While systems for sample collection and storage have become convenient and customizable, the use of automation in microbiology remains fairly limited. Contamination still remains a cause for concern, and protocols have to be rigorously outlined and implemented.

When you go to bed and how long you sleep at a time might actually make it difficult for you to stop worrying, according to researchers at Binghamton University. The study, led by Binghamton Anxiety Clinic Director Meredith Coles and graduate student Jacob Nota, found that people who sleep for shorter periods of time and go to bed very late at night are often overwhelmed with more negative thoughts than those who keep more regular sleeping hours. The findings appear in Springer’s journal Cognitive Therapy and Research, being published this month.

IBM's SoftLayer cloud-enabled World Community Grid to provide free virtual supercomputer power to The Scripps Research Institute to speed screening of promising chemical compounds.

A preliminary university investigation has revealed that University of Texas (UT) environmental health and safety officials disposed of multiple brain specimens in approximately 2002 in accordance with protocols concerning biological waste, according to a Dec. 3 statement by the school.













