CURRENT ISSUE | VOLUME 11 - ISSUE 2 | March 2016
COVER STORY
Regulatory Compliance
Dedication, resources, and manpower required
Editor's Buzz
Government regulations, like death and taxes, are an inescapable part of today’s laboratories
Lab Health and Safety
Laboratories are full of potentially hazardous minefields, and they don’t include just chemicals.
Leadership and Staffing
Developing a culture of open communication within an organization begins with the onboarding process.
As part of professional development and training programs, lab managers must be provided with opportunities to develop the skills required to effectively facilitate virtual collaborations.
Research-Specific Labs
For the Biotron Laboratory at the University of Wisconsin-Madison, varying temperatures and humidity levels are a good thing.
Business Management
Safety and quality are paramount to the food and beverage industry, but so is profitability.
Laboratory Technology
A great design can help you adapt to a lab’s changing needs and even play a major role in reducing the overall environmental impact.
COD analyzer designed to reduce costs for watewater treatment plants.
INSIGHTS
Next-generation (NGS) sequencing brings scalability and sensitivity to diagnostics in ways that traditional DNA analysis could not
In many cases metals can contaminate the environment, and scientists and public health workers rely on tools like ICP-MS to deliver accurate analysis.
Ask the Expert
Dr. Robert Linnen discusses the impact a compact SEM has had on his research.
Gary Siuzdak, PhD, discusses his work developing novel mass spectrometry-based approaches in metabolomics and nanostructure-based imaging.
Product Focus
Although most chemists take classes in the theory of gas chromatography (GC), they learn operation and troubleshooting mostly through hands-on operation and laboratory lore.
Nearly any biologist can now use some form of this microscopy
When choosing which lab stirrer option is best for you, it depends on the application
The ongoing changes in today’s microwave digesters make it possible for researchers to use these devices in more sophisticated ways
Surveys
High-performance liquid chromatography (HPLC) is, for many scientists, an essential chromatographic technique. HPLC systems used for the separation, identification, purification, and quantification of various chemical and biochemical solutions are composed of a pump, a sample injector, a separation column, a detection unit, and a data-processor.
Automated liquid handling (ALH) systems span the range from semi-automated multichannel pipettors to room-sized systems. The industry is trending toward versatile, modular ALH systems—seemingly for every budget. Likewise, instrumentation, software, and methods have followed the trend toward greater user accessibility.
Glove boxes go by many different names and are used for many purposes. However, their essential attribute is the ability to maintain a completely separate environment from ambient. Glove boxes are completely closed compartments ranging in size from a few cubic feet to several hundred cubic feet and differ from other safety enclosures in two significant respects: users can introduce articles into glove boxes and manipulate them inside through ports fitted with gloves, and glove boxes typically use a specialized atmosphere.
Whether to employ central washing stations or point-of-use washers located under a lab bench or in a corner is something that has to be addressed with regards to laboratory glassware washers. The former provide an economy of scale and are popular with lab workers who, almost universally, hate to “wash the dishes.” The downside for central washing stations is that glassware tends to disappear over time, due to breakage and operator error.
How it Works
Problem: Nearly 40 years after its introduction, western blotting continues to be a powerful method for protein quantitation. Arguably, finding the right antibody to detect the protein of interest is the technique’s most critical and challenging step.
Problem: The topic of technology transfer raises caution with many laboratory managers of analytical laboratories. In routine analysis laboratories, such as QA/QC, the need for continued support of established high performance liquid chromatography (HPLC) methods can significantly outweigh the potential advantages of method modernization, making it exceptionally problematic or undesirable to adopt more modern liquid chromatography (LC) assays or instrumentation such as U(H)PLC ultra-high performance LC.