Human cells make new copies of their DNA billions of times each day, a crucial process upon which life itself depends. However, scientists do not fully understand how cells unzip the double-stranded DNA molecule before replicating both halves of it. New work at Rockefeller may help change that.

Researchers use new techniques to document how cells can conceal growth and then suddenly swell up. The study is a paradigm shift in understanding "osmotic shock" and may lead to new strategies for fighting bacterial diseases.

On May 9, the Global Medical Excellence Cluster (GMEC) announced a five-year collaborative agreement with Pfizer Inc. that provides a framework for the research and development of new and innovative medicines for rare diseases.

Before doctors like Matthias Kretzler can begin using the results of molecular research to treat patients, they need science to find an effective way to match genes with the specific cells involved in disease. As Kretzler explains, finding that link would eventually let physicians create far more effective diagnostic tools and treatments.

A new sweat test for cystic fibrosis developed at Stanford University produces more detailed information than before, which may aid treatment of the disease.

Discovery of a novel reprogramming method of adult cells could shift stem cell research.

OAK RIDGE, Tenn., Dec. 17, 2013— If scientists can control cellular functions such as movement and development, they can cripple cells and pathogens that are causing disease in the body.

The probe mimics pathogen's amino acids, solving mystery behind Chlamydiae cell wall.