Gary W. Procop, MD, MS, chair of the Department of Molecular Pathology, section head of molecular microbiology, and director of mycology and parasitology at the Cleveland Clinic, talks to contributing editor Tanuja Koppal, PhD, about the clinic’s $75 million state-of-the-art medical testing laboratory that opened in 2012. The building houses microbiology, molecular pathology, cytogenetics, and immunopathology as well as administrative offices. He talks about the thinking that went into designing the building and its labs and shares some insights on what people need to consider when embarking on such initiatives, however small or large. He emphasizes that both people and laboratories should always be open to change, making way for new advancements in science and technology.

Angelo Filosa, PhD, associate director in chemistry and head of Analytical Chemistry and Compound Management at Boehringer Ingelheim (Canada) Ltd., discusses the pros and cons of consolidating the servicing of all his laboratory equipment with one vendor.

Scott Martin, Ph.D., team leader for RNA interference (RNAi) screening at the National Institutes of Health, Center for Advancing Translational Sciences, talks to contributing editor Tanuja Koppal, Ph.D., about recent trends in the use of different types of cells and reagents for screening drug targets and cellular pathways.

Matthew Sullivan, an environmental specialist in the Field Operations section of the Bureau of Environmental Services for the city of Portland, Oregon, talks to contributing editor Tanuja Koppal, Ph.D., about how field testing, particularly for water analysis, has changed over the years. The testing equipment is now better suited for field analysis, in terms of its size, compactness, and robustness. The newer instruments have also allowed for sampling and testing to be done remotely and in an automated fashion. Overall, field instrumentation is striving to provide faster, cheaper, more robust, and more real-time measurements for routine analysis.

Joel Dudley, Ph.D., Assistant Professor of Genetics and Genomic Sciences and Director of Biomedical Informatics at Mount Sinai School of Medicine, talks to contributing editor Tanuja Koppal, Ph.D. about the current changes impacting bioinformatics.

Dr. Amanda Capes-Davis, an independent cell culture consultant and founding manager of CellBank Australia, talks to contributing editor Tanuja Koppal, PhD, about the imperative need to establish best practices in a cell culture laboratory.

Steven Wolk, PhD, associate director of analytical chemistry at SomaLogic Inc., discusses the use of high-performance liquid chromatography (HPLC) and ultra high-performance (or pressure) liquid chromatography (UHPLC) technologies for analytical work.

Alexander Sherman, director of systems in the Department of Neurology and director of strategic development and systems at the Neurological Clinical Research Institute at Massachusetts General Hospital, discusses why the right choice and setup for data collecting, data handling, and data sharing infrastructure is important to help establish successful research collaborations.

George Weinstock, Ph.D., professor of Genetics and Molecular Microbiology at Washington University, discusses what a lab manager can do to stay abreast of changes in the rapidly evolving field of next-generation sequencing.

Sarah Haviland, lab manager and graduate student in the Department of Regenerative Medicine and Cell Biology at the Medical University of South Carolina, shares her experiences with contributing editor Tanuja Koppal, Ph.D., on choosing and installing a new point-of-use water purification system.

Contributing editor Tanuja Koppal, Ph.D., talks to two scientists—one from a large pharmaceutical company and the other from a large academic institution—about their experiences with transitioning from paper to electronic lab notebooks (ELNS).

Allis Chien, Ph.D., director of the Vincent Coates Foundation Mass Spectrometry Laboratory at Stanford University’s mass spectrometry shared core resource facility, discusses the advances being made in the instrumentation and applications for mass spectrometry (MS).