Whitepaper

Although gold nanoparticle production can be controlled to yield specific size ranges, both the concentration and size of nanoparticles must be checked following production. UV-Vis spectrophotometry is an established QC method for this; however cuvette spectrophotometers often require dilution of the nanoparticle solution before measuring, and volumes up to 3 mL.

With the expansion of the global nutraceutical market, the spotlight on the analysis of its raw materials is ever increasing. Testing of nutraceutical products for heavy metals like lead, arsenic, cadmium and mercury has gained utmost importance. Extremely low levels of these heavy metals like mercury, in nutraceuticals make its analysis challenging.

Solvent removal from solutions is commonly performed in laboratory and production processes. There are a number of different methods that can be used for solvent removal, including evaporation, vacuum concentration, lyophilization, reverse extraction, solute precipitation, and dialysis (solvent exchange).

This Application Note will demonstrate the extraction of 1,4-Dioxane from an aqueous matrix using Option 1 of EPA Method 522 for 500 mL initial volume sample. It will make use of the SmartPrep Cartridge Extraction System to produce a valid Initial Demonstration of Precision (IDP) and Initial Demonstration of Accuracy (IDA).









