Biological Sciences

Linsey Marr, a professor in the Charles E. Via Jr. Department of Civil and Environmental Engineering at Virginia Tech, is obsessed with flu transmission.

Stanford University announced Jan. 29 that it has received a grant from the Bill & Melinda Gates Foundation to accelerate efforts in vaccine development. The $50 million grant over 10 years will build on existing technology developed at Stanford and housed in the Human Immune Monitoring Core, and will establish the Stanford Human Systems Immunology Center. The center aims to better understand how the immune system can be harnessed to develop vaccines for the world's most deadly infectious diseases.

Salk scientists discover how a "mini-brain" in the spinal cord aids in balance.

Sites where DNA is damaged may cause a molecule that slides along the DNA strand to scan for damage to slow on its patrol, delaying it long enough to recognize and initiate repair. The finding suggests that the delay itself may be the key that allows the protein molecule to find its target, according to researchers at the University of Illinois at Chicago.

In a new study, Sanford-Burnham Medical Research Institute researchers have used human pluripotent stem cells to generate new hair. The study represents the first step toward the development of a cell-based treatment for people with hair loss. In the United States alone, more than 40 million men and 21 million women are affected by hair loss. The research was published online in PLOS ONE.

Ribonucleotides, units of RNA, can become embedded in genomic DNA during processes such as DNA replication and repair, affecting the stability of the genome by contributing to DNA fragility and mutability. Scientists have known about the presence of ribonucleotides in DNA, but until now had not been able to determine exactly what they are and where they are located in the DNA sequences.

As many as 1.4 million Americans suffer from uncomfortable abdominal cramping and diarrhea that come with ulcerative colitis and Crohn’s disease. These conditions, collectively known as inflammatory bowel disease (IBD), are associated with an imbalance among the thousands of species of “good” bacteria that inhabit the gut. A University of Utah study published on Jan. 22, 2015, in Cell Host and Microbe demonstrates that mice deficient for a component of the immune system, a protein called MyD88, have an imbalanced gut bacterial community – with some species dominating over others - and are more susceptible to contracting a severe IBD-like illness. Further, fecal transplants from healthy donors alleviate IBD symptoms in these mice.

Five genetic variants that influence the size of structures within the human brain have been discovered by an international team that included a Georgia State University researcher.












