Sukhanya Jayachandra, Ph.D., Senior Research Investigator and head of the Cellular Resource Group, Lead Discovery Profiling Compound Management at Bristol-Myers Squibb (BMS), discusses her cell culture core facility.

Thanks to work at LLNL, sub-three-minute amplification of DNA and RNA via polymerase chain reaction (PCR) is now possible.

Microvolume assessment of bacterial culture growth was found to facilitate measurement of undiluted cultures. Comparison between microvolume and cuvette-based data requires the use of a conversion factor, which can be simply determined.

Ralph Garippa, Ph.D., independent consultant and former head of cell-based high-throughput screening (HTS) and microscopic imaging-based high-content screening (HCS) at Hoffmann-La Roche, discusses the recent trends in cell culture.

Problem: Mass spectrometry (MS) has become an indispensible technology for the analysis of compounds of biological interest, is widely available and offers rapid and accurate detection with broad applicability.

A few of the essential dos and donts of cell culture are mandatory; e.g. use of personal protective equipment (PPE). Many of them are common sense and apply to all laboratory areas. However some of them are specific to tissue culture.

Dr. Peter Hodder, senior scientific director and head of Lead Identification Division at The Scripps Research Institute in Florida, talks about his experiences moving from big pharma to academia to set up a high-throughput screening laboratory from the ground up.

Showing movies in 3-D has produced a box-office bonanza in recent months. Could viewing cell behavior in three dimensions lead to important advances in cancer research? A new study led by Johns Hopkins University engineers indicates it may happen. Looking at cells in 3-D, the team members concluded, yields more accurate information that could help develop drugs to prevent cancers spread.

The latest innovation in cell counting combines the ease of automated instrumentation and the accuracy of Coulter technology in an affordable, hand-held format.

3D Biotek developed a Fabrication Program with Microsoft .NET technology that accepts as input basic parameters of the scaffold, such as the outer dimensions and pore size.

The most widely used human embryonic stem cell lines lack genetic diversity, a finding that raises social justice questions that must be addressed to ensure that all sectors of society benefit from stem cell advances, according to a University of Michigan research team.

IDT has recently developed its PrimeTime qPCR assay portfolio. This complete range of assay scales enables more affordable gene studies which better reflect the needs of the customer.