Article
Screw cap tubes are found in the vast majority of laboratories and are commonly used for the long-term storage and cryopreservation of a plethora of sample types. Effectively maintaining sample integrity in these storage environments is of extreme importance to any researcher, and there are key factors that require consideration.
All contemporary, as well as NextGen and Third Generation sequencing methodologies are dependent on the generation of DNA fragments from initial MegaBase long chromosomal DNA molecules. General requirements are that such fragments have to be random and of similar size.
Significant time and effort is expended in screening chemical and biological sample libraries. However, no matter how advanced the screening system, the end results are only as good as the quality of the sample in the microplate wells.
Excessive background from endogenous sample matrix components has always been of great concern in bioanalysis, and has become paramount today with the need for decreasing analytical run times.
Many experienced lab technicians are aware of the sweet spot in their oven or incubator–the back right-hand corner of the middle shelf where their experiment or process always comes out right.
Whether by training and education or by moving up through the ranks of their respective organizations, fortunate research professionals make their way into fields that offer meaningful work and the opportunity to use their skills to contribute to society.
Multi-vendor service models continue to evolve in order to address changing customer and market needs, such as the increasing need for asset utilization data that is vendor independent.
One of the best approaches for proactively managing obsolescence is to develop and maintain a multiyear capital plan that explicitly designates a specific portion for instrument replacement each year.
A change in behavior, in attitude or in lifestyle is not easy to achieve, and some seem near impossible. However, the change process can be understood, and change can be implemented more successfully and more reliably by following a few rules.
David Hachey, Ph.D., talks about his role as the director of both the mass spectrometry and proteomics core laboratories at Vanderbilt University.
Despite the vigilance of federal, state and local regulators and of accreditation organizations that evaluate and certify laboratories, the development and maintenance of quality in laboratories are constant concerns.
