Article

Problem: Scientists must typically rely on high-end cell sorters in core facilities to run their samples. These cell sorters—equipped with five or more lasers and double digit detection channels—were originally utilized to answer pressing questions arising in the immunology field. However, they are overly complex for the new breed of user who sorts cells today: cell biologists and biochemists who employ fluorescent proteins and require at most four colors and one-to-two population sorting. The challenge is that as demand increases, the number of staff available to operate these complex instruments remains the same. As a result, wait times at core facilities have ballooned, literally putting research on hold until capacity is available. For the more than half of today’s cell sorting users who require four colors or
fewer sorts, the elaborate equipment is becoming a bottleneck.

Problem: Achieving successful PCR (polymerase chain reaction) results requires proper control of many factors and parameters. The yield—quantity and quality—of amplified DNA is often essential for downstream applications and ultimately successful completion of experimental research. PCR reagents, consumable sample vessels, and the thermal cycler instrument must all be properly chosen for the specific PCR application, and must also meet quality and performance requirements. In addition to these components that must work correctly in conjunction, sample preparation is typically done manually and must be done with care and accuracy.

Problem: An emergency spill response plan is part of every laboratory safety protocol. However, despite all the best precautions, accidents can happen! Laboratories often house chemicals such as acids, bases, solvents and flammables—all of which can be toxic to human health and the environment if used incorrectly or spilled.

The barbarians were at the gates, the handwriting on the wall. Their digital firepower was unstoppable.
Without further ado, they stormed the ramparts, overrunning scientific strongholds. There is no turning back now. Social media is a juggernaut, its impact profound and already making itself felt in ways that few could have envisioned.

No matter what field you serve, your role as a modern laboratory manager requires an intimate understanding of how safety, productivity, and sustainability work together to determine the success of your entire operation in achieving accurate results and containing costs. It’s no surprise that one of the biggest challenges of running a successful lab operation is meeting all these expectations without sacrificing any one of them.















