
CURRENT ISSUE | VOLUME 10 - ISSUE 4 | May 2015
COVER STORY
Remote Control
Latest lab apps allow researchers to access their instruments from almost anywhere
Laboratory Technology
Business Management

A barely-known junior senator from Illinois becomes the first African American elected President of the United States. A 19-year-old Pittsburgh entrepreneur strikes a $100,000 deal with Shark Tank investor Mark Cuban and turns a small business into a multi-million dollar company. A former advertising executive sells rocks as hassle-free pets and creates an estimated $15 million dollar profit in six months.

When HR professionals talk about rewards and recognition in the workplace, it’s easy to hit the default button that leads directly to bonuses or “attaboys.” After all, every employee appreciates a nice check or a public pat on the back for a job well done, right? Incentivizing workers this way definitely has a long-standing place in generating goodwill and improving morale with employees.
Leadership and Staffing
Lab Health and Safety
Lab Health and Safety Tips
Ask the Expert

Douglas Kiehl is a principal research scientist at Eli Lilly & Company, and is currently leader for the Spectroscopy & Raw Materials team. His group performs characterization and structural elucidation of impurities, related substances, and contaminants as well as testing and qualification of process raw materials through development and commercialization. Additionally, his team leads Lilly’s technical strategy for evaluating extractables and leachables associated with pharmaceutically relevant materials.

Dr. Donald Sakaguchi, professor of genetics, development and cell biology at Iowa State University, talks to contributing editor Dr. Tanuja Koppal about the time and cost savings generated in his lab due to a recent investment in a high-content screening (HCS) system. While his research group can now set up more experiments to look at different cell types and conditions, they also spend more time carefully designing the experiments and optimizing the conditions and later analyzing the vast amounts of data generated from each experiment.
INSIGHTS

Combining chromosomes from different organisms started as soon as someone created a hybrid. “In natural breeding,” says geneticist Kulvinder S. Gill of Washington State University in Pullman, “we transfer genes through hybridization—transferring pollen from one plant to another.” He adds, “It can, for example, be pollen from wheat to rye or rye to wheat.”
Product Focus


Cell-based assays have become the go-to technology for pharmaceutical, environmental, and toxicology labs. Cells are far less costly to maintain than test animals and don’t involve the ethical considerations. But the complexity of cell-based assays compared with chemical or biochemical assays presents distinct challenges to laboratory managers.

When implementing laboratory informatics systems, managers should consider both current and anticipated workflows, says Trish Meek, director of product strategy at Thermo Fisher Scientific (Waltham, MA). “They need complete agreement and buy-in from business owners and IT. Managers should consider the agility their business requires, for example, when bringing in a new product or instrument.”
Surveys

Ultraviolet-visible (UV-Vis) spectrophotometry is arguably the most common as well as one of the oldest forms of absorption-based analysis. UV and visible regions of the electromagnetic spectrum are contiguous: UV wavelengths range from 10 to 4000 angstroms; they are visible from 4000 to 7000 angstroms.

Vacuum pumps are an essential piece of equipment and are used in a wide variety of processes in most laboratories. Over the past 25 years, it has become apparent that vendors have made significant innovative improvements to vacuum pumps, with important developments in high vacuum technology, corrosion resistance, vacuum control, and improvements in the efficiency and ecological impact of vacuum pumps.
Products in Action

In KPMG’S 2014 Food, Drink and Consumer Goods Industry Outlook Survey, 22 percent of the senior managers questioned said that “staying ahead of or navigating changes in the regulatory environment” would consume most of their time in the coming 12 months. Nearly 20 percent said that geographic expansion would be one of the primary areas of investment in the coming months. Taken together, these two data points echo a common food industry refrain: we want to expand internationally, but we’re increasingly aware of the difficulties and costs of doing so from a regulatory standpoint.

Thawing cells in a regulated environment presents many challenges. The need to minimize variability through standardization is crucial. Whereas the science of cell freezing has become highly standardized in order to improve and retain optimal viability and function, cell thawing has been overlooked and has much to gain from similar standardization.

Abstract: A new Type of Class II BSC has emerged that will simplify the selection process and provide true flexibility in modern laboratories needing both chemical and biological protection. Along with 3rd party validation in biological challenges by NSF International®, the Purifier Axiom Class II BSC was put under
ASHRAE 110 containment testing for chemical hazards to verify its ability to handle chemical hazards as well as a fume hood.

Inductively coupled plasma optical emission spectrometry (ICP-OES) is used for elemental analysis of everything from soil and sludge to water and wastewater, plus various industrial process materials. In evaluating ICP-OES instruments, environmental contract laboratories may prioritize sensitivity and speed. Industrial research laboratories may emphasize stability and analytical precision. However, both agree on the importance of controlling costs.

Gel permeation chromatography (GPC) is the most widely accepted and used analytical method for obtaining molar mass averages of both synthetic and biopolymers. Traditionally, molar mass averages are obtained via a peak position calibration involving a series of standards of known molar mass and chemistry analyzed by GPC coupled to a differential refractive index (RI) detector.






















