Although most chemists take classes in the theory of gas chromatography (GC), they learn operation and troubleshooting mostly through hands-on operation and laboratory lore.
The most significant equipment-related trend in bioprocessing over the past 15 years has been the replacement of reusable glass and steel equipment by single-use plastics.
Chromatographers often need to balance the convenience of universal-use columns against the sensitivity and resolution of specialized columns. “Where labs may at one time have employed a nonpolar, all-purpose column, they now seek columns engineered for chemical families or even specific methods,” says Timothy Anderson, GC products manager at Phenomenex (Torrance, CA).
As regulators have redefined environmental methods for low-abundance analytes, and demanded the analysis of more analytes, column manufacturers have done well to provide greater sensitivity and selectivity.
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