Product Resource: Applications

Combinatorial chemistry can be traced back to the 1960's, but didn't gain popularity until 1990 when pharmaceutical companies started compounding large amounts of potential new drugs into libraries. Now, combinatorial chemistry has moved into other disciplines such as materials science, biotechnology and even semiconductors

With its new 875 Karl Fischer Gas Analyzer, Metrohm combines decades of experience in moisture analysis and sample handling. The KF Gas Analyzer is designed to handle nearly any gas sample - compresses, liquefied or native. It is fully equipped to measure the absolute moisture content of LPG, petrochemical intermediates, natural gas or other compresses or liquefied gases.

Problem: With unrelenting need for accurate sample analysis at lower and lower detection limits, there is pressure on modern laboratories for sample prep instruments that can provide automated, accurate reagent additions to previously prepared liquid samples or for preparing several aliquots of these samples with multiple dilution factors. The catch-all phrase that identifies these devices is “liquid handling systems” and they perform absolutely essential tasks that have a direct and large effect on the ultimate measurement accuracy of both inorganic and organic sample analysis.

Food testing labs have traditionally used conventional PCR and quantitative real-time PCR (qPCR) to detect the presence of genetically modified organisms (GMOs) in food and feed. When quantification is required, GMO content in these samples is expressed in relative terms as the ratio of the quantity of the transgene, which is the nucleic acid fragment introduced in the host genome, to that of an endogene, a gene normally found in the host genome.

Gas generators have become an alternative to high-pressure gas cylinders for supplying laboratory applications with high purity hydrogen, nitrogen, and zero-air. Until now, there has been no generator option for supplying high purity oxygen. Small pressure swing adsorption (PSA)-based oxygen generators are available for medical applications but do not offer the high purity generally required in the laboratory.

Since its introduction in 2011, Bio-Rad Laboratory’s Droplet Digital PCR (ddPCR™) technology has demonstrated the potential to be a transformative technology, particularly in clinical applications. At the second annual CHI Digital PCR Conference in San Diego, CA, Oct. 7–9, 2013, 12 scientists using Bio-Rad’s Droplet Digital PCR systems will highlight ddPCR applications that have advanced their research.









