This application note shows how UltraPerformance Convergence Chromatography combined with ESI-MS/MS enabled the simultaneous profiling of 25 bile acids within 13 minutes.

Growing plants in a microscope is helping scientists to view roots developing in 3D and in real time.

Amrita Cheema, PhD, associate professor and codirector of the Proteomics and Metabolomics Shared Resource at Georgetown University Medical Center, talks to contributing editor Tanuja Koppal, PhD, about the growing use of mass spectrometry as a tool for detecting biomarkers for early prediction and diagnosis of disease, leading to personalized therapy. She highlights that improvements in software
and hardware have led to better resolution and specificity, which in turn have increased the use of this technology for biomarker discovery and will potentially help pave its path into the clinic as a diagnostic tool.

A forensics investigator dusts a crime scene for fingerprints. When she finds one, she reaches to her holster, pulls out a handheld device, and aims it at the fingerprint. The device captures the image and also the chemical composition. That chemical analysis reveals that the person who left the print had touched ephedrine—an illegal drug, which is a stimulant that goes by many street names, including meow. With this information, the investigators can use biometrics—the fingerprint— to identify the person and the chemical analysis to start piecing together the crime.

Automated solution unlocks the power of clinical data and accelerates LC-MS/MS workflows.

Particles of soot floating through the air and comets hurtling through space have at least one thing in common: 0.36. That, reports a research group at the National Institute of Standards and Technology (NIST), is the measure of how dense they will get under normal conditions, and it’s a value that seems to be constant for similar aggregates across an impressively wide size range from nanometers to tens of meters.*

Study to form part of a “Science behind the World Cup” special feature.

Particle sizing methodologies range from straightforward sieving and sedimentation analysis to advanced laser-based light scattering techniques, microscopy/imaging, nanoparticle tracking analysis, and others.

New research reveals how the algae behind red tide thoroughly disables – but doesn’t kill – other species of algae. The study shows how chemical signaling between algae can trigger big changes in the marine ecosystem.

The new Metals Lab involves a multiscale, three-dimensional correlative imaging workflow to better understand and develop metallic alloys for the automotive, aerospace, nuclear, and oil & gas industries.

Ferroelectric materials–substances in which there is a slight and reversible shift of positive and negative charges–have surfaces that are coated with electrical charges like roads covered in snow.  Accumulations can obscure lane markings, making everyone unsure which direction traffic ought to flow; in the case of ferroelectrics, these accumulations are other charges that “screen” the true polarization of different regions of the material.

Dr. Zhaozheng Yin, an assistant professor of computer science at Missouri University of Science and Technology, recently received the National Science Foundation’s most prestigious award for young faculty members for his research into developing algorithms and systems for processing microscopy images of biological specimens.