Advances enhance performance of mass spectrometers.

Scientists at Albert Einstein College of Medicine of Yeshiva University and their international collaborators have developed a novel fluorescence microscopy technique that for the first time shows where and when proteins are produced. The technique allows researchers to directly observe individual messenger RNA molecules (mRNAs) as they are translated into proteins in living cells. The technique, carried out in living human cells and fruit flies, should help reveal how irregularities in protein synthesis contribute to developmental abnormalities and human disease processes including those involved in Alzheimer’s disease and other memory-related disorders. The research will be published the March 20 edition of Science. 

Vanderbilt University researchers have achieved the first “image fusion” of mass spectrometry and microscopy — a technical tour de force that could, among other things, dramatically improve the diagnosis and treatment of cancer.

Sports is big business, which is why leagues and federations are desperate to keep their franchises honest. In the US, Major League Baseball (MLB) received a record $9 billion in revenues in 2014, while the National Football League took in close to $10 billion. 

Problem: In the analytical sciences the common image of mass spectrometry involves researchers in a core facility, analyzing spectra generated by a machine the size of a refrigerator. Because conventional mass spectrometers operate under extreme vacuum, they must be coupled with pumps that are expensive, bulky, noisy, and fragile. These powerhouse systems are designed to accommodate a wide variety of often-disparate needs, and this flexibility adds complexity in both operation and maintenance.

Dr. Guido Verbeck discusses recent developments in mass spectrometry with contributing writer Tanuja Koppal, PhD

Advances in computer hardware and software, data storage and processing, optics, systems and instrumentation, labeling agents, and reagents have all contributed to the current surge in imaging in the life sciences.

Berkeley Lab research provides comprehensive description of ultra-small bacteria.

Clinicians and patients alike know that traditional cancer treatments beat up the person as much as the cancer. Success arises only if the treatment kills the cancer before the patient. For decades, researchers sought solutions that attacked only the cancer, not healthy tissue.

Two cannabis testing labs from Colorado share their thoughts on how the state’s emerging recreational marijuana industry has affected them.

Delivering the capability to image nanostructures and chemical reactions down to nanometer resolution requires a new class of x-ray microscope that can perform precision microscopy experiments using ultra-bright x-rays from the National Synchrotron Light Source II (NSLS-II) at Brookhaven National Laboratory. This groundbreaking instrument, designed to deliver a suite of unprecedented x-ray imaging capabilities for the Hard X-ray Nanoprobe (HXN) beamline, brings researchers one step closer to the ultimate goal of nanometer resolution at NSLS-II, a U.S. Department of Energy Office of Science User Facility.

A research team led by North Carolina State University has identified and synthesized a material that can be used to create efficient plasmonic devices that respond to light in the mid-infrared (IR) range. This is the first time anyone has demonstrated a material that performs efficiently in response to this light range, and it has applications in fields ranging from high-speed computers, to solar energy to biomedical devices.