
CURRENT ISSUE | VOLUME 7 - ISSUE 10 | November 2012
COVER STORY
Toot Your Own Horn
Aggressive self-promotion might just be the scientific community's saving grace
Surveys
Laboratory Technology
Products in Action

The 2010 Geno/Grinder® offers analysts a versatile high-throughput tissue homogenizer for plant or animal tissue homogenization. The patented design with a true linear grinding motion provides the most efficient bead milling mechanism for tissue homogenization and cell lysis for extraction of DNA, RNA, proteins or enzymes.

White Papers and Application Notes

Although gold nanoparticle production can be controlled to yield specific size ranges, both the concentration and size of nanoparticles must be checked following production. UV-Vis spectrophotometry is an established QC method for this; however cuvette spectrophotometers often require dilution of the nanoparticle solution before measuring, and volumes up to 3 mL.

With the expansion of the global nutraceutical market, the spotlight on the analysis of its raw materials is ever increasing. Testing of nutraceutical products for heavy metals like lead, arsenic, cadmium and mercury has gained utmost importance. Extremely low levels of these heavy metals like mercury, in nutraceuticals make its analysis challenging.

Solvent removal from solutions is commonly performed in laboratory and production processes. There are a number of different methods that can be used for solvent removal, including evaporation, vacuum concentration, lyophilization, reverse extraction, solute precipitation, and dialysis (solvent exchange).

This Application Note will demonstrate the extraction of 1,4-Dioxane from an aqueous matrix using Option 1 of EPA Method 522 for 500 mL initial volume sample. It will make use of the SmartPrep Cartridge Extraction System to produce a valid Initial Demonstration of Precision (IDP) and Initial Demonstration of Accuracy (IDA).
How it Works

Choosing an in vitro model system that faithfully represents the natural physiology of the cell being studied is fundamental to understanding its in vivo function. Cultures of primary cell isolates retain their physiology and karyotype after isolation, but cultures may be difficult to prepare and are susceptible to contamination.

Basic research and clinical research labs have long relied on real-time PCR (qPCR) for its speed, sensitivity, specificity and ease-of-use. Common applications include gene expression analysis, mutation detection and identification of copy number variation to better understand inherited disorders, cancer and infectious disease.













